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Mitochondria-Derived Superoxide Links to Tourniquet-Induced Apoptosis in Mouse Skeletal Muscle

Our previous study has reported that superoxide mediates ischemia-reperfusion (IR)-induced necrosis in mouse skeletal muscle. However, it remains poorly understood whether IR induces apoptosis and what factors are involved in IR-induced apoptosis in skeletal muscle. Using a murine model of tournique...

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Detalles Bibliográficos
Autores principales: Tran, Thai P., Tu, Huiyin, Liu, Jinxu, Muelleman, Robert L., Li, Yu-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422247/
https://www.ncbi.nlm.nih.gov/pubmed/22912870
http://dx.doi.org/10.1371/journal.pone.0043410