Genetic Variation in the Plasmodium falciparum Circumsporozoite Protein in India and Its Relevance to RTS,S Malaria Vaccine

RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region and the complete C-terminal T cell epitope region (Th2R and Th3R) of the circumsporozoite protein (CSP). Since natu...

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Detalles Bibliográficos
Autores principales: Zeeshan, Mohammad, Alam, Mohammad Tauqeer, Vinayak, Sumiti, Bora, Hema, Tyagi, Rupesh Kumar, Alam, Mohd Shoeb, Choudhary, Vandana, Mittra, Pooja, Lumb, Vanshika, Bharti, Praveen Kumar, Udhayakumar, Venkatachalam, Singh, Neeru, Jain, Vidhan, Singh, Pushpendra Pal, Sharma, Yagya Dutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422267/
https://www.ncbi.nlm.nih.gov/pubmed/22912873
http://dx.doi.org/10.1371/journal.pone.0043430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422267/
https://www.ncbi.nlm.nih.gov/pubmed/22912873
http://dx.doi.org/10.1371/journal.pone.0043430

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