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Exercise Does Not Protect against MPTP-Induced Neurotoxicity in BDNF Happloinsufficent Mice
Exercise has been demonstrated to potently protect substantia nigra pars compacta (SN) dopaminergic neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. One mechanism proposed to account for this neuroprotection is the upregulation of neurotrophic factors. Several...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422268/ https://www.ncbi.nlm.nih.gov/pubmed/22912838 http://dx.doi.org/10.1371/journal.pone.0043250 |