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Exercise Does Not Protect against MPTP-Induced Neurotoxicity in BDNF Happloinsufficent Mice

Exercise has been demonstrated to potently protect substantia nigra pars compacta (SN) dopaminergic neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. One mechanism proposed to account for this neuroprotection is the upregulation of neurotrophic factors. Several...

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Detalles Bibliográficos
Autores principales:	Gerecke, Kim M., Jiao, Yun, Pagala, Viswajeeth, Smeyne, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422268/ https://www.ncbi.nlm.nih.gov/pubmed/22912838 http://dx.doi.org/10.1371/journal.pone.0043250

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