An Improved Protocol for Sequencing of Repetitive Genomic Regions and Structural Variations Using Mutagenesis and Next Generation Sequencing

The rise of Next Generation Sequencing (NGS) technologies has transformed de novo genome sequencing into an accessible research tool, but obtaining high quality eukaryotic genome assemblies remains a challenge, mostly due to the abundance of repetitive elements. These also make it difficult to study...

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Detalles Bibliográficos
Autores principales: Sipos, Botond, Massingham, Tim, Stütz, Adrian M., Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422288/
https://www.ncbi.nlm.nih.gov/pubmed/22912860
http://dx.doi.org/10.1371/journal.pone.0043359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422288/
https://www.ncbi.nlm.nih.gov/pubmed/22912860
http://dx.doi.org/10.1371/journal.pone.0043359

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