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Intravenous Grafts Of Amniotic Fluid-Derived Stem Cells Induce Endogenous Cell Proliferation and Attenuate Behavioral Deficits in Ischemic Stroke Rats

We recently reported isolation of viable rat amniotic fluid-derived stem (AFS) cells [1]. Here, we tested the therapeutic benefits of AFS cells in a rodent model of ischemic stroke. Adult male Sprague-Dawley rats received a 60-minute middle cerebral artery occlusion (MCAo). Thirty-five days later, a...

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Detalles Bibliográficos
Autores principales: Tajiri, Naoki, Acosta, Sandra, Glover, Loren E., Bickford, Paula C., Jacotte Simancas, Alejandra, Yasuhara, Takao, Date, Isao, Solomita, Marianna A., Antonucci, Ivana, Stuppia, Liborio, Kaneko, Yuji, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422299/
https://www.ncbi.nlm.nih.gov/pubmed/22912905
http://dx.doi.org/10.1371/journal.pone.0043779