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Mutant Amyloid Precursor Protein Differentially Alters Adipose Biology under Obesogenic and Non-Obesogenic Conditions

Mutations in amyloid precursor protein (APP) have been most intensely studied in brain tissue for their link to Alzheimer’s disease (AD) pathology. However, APP is highly expressed in a variety of tissues including adipose tissue, where APP is also known to exhibit increased expression in response t...

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Detalles Bibliográficos
Autores principales: Freeman, Linnea R., Zhang, Le, Dasuri, Kalavathi, Fernandez-Kim, Sun-Ok, Bruce-Keller, Annadora J., Keller, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422309/
https://www.ncbi.nlm.nih.gov/pubmed/22912823
http://dx.doi.org/10.1371/journal.pone.0043193