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Safety in glomerular numbers

A low nephron number is, according to Brenner’s hyperfiltration hypothesis, associated with hypertension, glomerular damage and proteinuria, and starts a vicious cycle that ends in renal failure over the long term. Nephron endowment is set during foetal life, and there is no formation of nephrons af...

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Detalles Bibliográficos
Autor principal: Schreuder, Michiel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422453/
https://www.ncbi.nlm.nih.gov/pubmed/22532329
http://dx.doi.org/10.1007/s00467-012-2169-x