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Prenatal Synthetic Glucocorticoid Treatment Changes DNA Methylation States in Male Organ Systems: Multigenerational Effects

Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of delivering preterm, approximately 10% of all pregnancies. Animal studies have demonstrated that offspring exposed to elevated glucocorticoids, either by administration of sGC or as a result of maternal stress, are...

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Detalles Bibliográficos
Autores principales: Crudo, Ariann, Petropoulos, Sophie, Moisiadis, Vasilis G., Iqbal, Majid, Kostaki, Alisa, Machnes, Ziv, Szyf, Moshe, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422463/
https://www.ncbi.nlm.nih.gov/pubmed/22564977
http://dx.doi.org/10.1210/en.2011-2160