Cargando…
Prenatal Synthetic Glucocorticoid Treatment Changes DNA Methylation States in Male Organ Systems: Multigenerational Effects
Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of delivering preterm, approximately 10% of all pregnancies. Animal studies have demonstrated that offspring exposed to elevated glucocorticoids, either by administration of sGC or as a result of maternal stress, are...
Autores principales: | Crudo, Ariann, Petropoulos, Sophie, Moisiadis, Vasilis G., Iqbal, Majid, Kostaki, Alisa, Machnes, Ziv, Szyf, Moshe, Matthews, Stephen G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422463/ https://www.ncbi.nlm.nih.gov/pubmed/22564977 http://dx.doi.org/10.1210/en.2011-2160 |
Ejemplares similares
-
Transgenerational Effects of Prenatal Synthetic Glucocorticoids on Hypothalamic-Pituitary-Adrenal Function
por: Iqbal, Majid, et al.
Publicado: (2012) -
Acute Glucocorticoid Administration Rapidly Suppresses Basal and Stress-Induced Hypothalamo-Pituitary-Adrenal Axis Activity
por: Andrews, Marcus H., et al.
Publicado: (2012) -
Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain
por: Qian, Xiaoxiao, et al.
Publicado: (2012) -
Central Nervous System (CNS) Delivery of Glucocorticoids Is Fine-Tuned by Saturable Transporters at the Blood-CNS Barriers and Nonbarrier Regions
por: Mason, Brittany L., et al.
Publicado: (2010) -
An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
por: Bentley, Liz, et al.
Publicado: (2014)