Three-Dimensional RNA Structure Refinement by Hydroxyl Radical Probing
Molecular modeling guided by experimentally-derived structural information is an attractive approach for three-dimensional structure determination of complex RNAs that are not amenable to study by high-resolution methods. Hydroxyl radical probing (HRP), performed routinely in many laboratories, prov...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422565/ https://www.ncbi.nlm.nih.gov/pubmed/22504587 http://dx.doi.org/10.1038/nmeth.1976 |