Three-Dimensional RNA Structure Refinement by Hydroxyl Radical Probing

Molecular modeling guided by experimentally-derived structural information is an attractive approach for three-dimensional structure determination of complex RNAs that are not amenable to study by high-resolution methods. Hydroxyl radical probing (HRP), performed routinely in many laboratories, prov...

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Detalles Bibliográficos
Autores principales: Ding, Feng, Lavender, Christopher A., Weeks, Kevin M., Dokholyan, Nikolay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422565/
https://www.ncbi.nlm.nih.gov/pubmed/22504587
http://dx.doi.org/10.1038/nmeth.1976