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Requirement of CD4 Help for Induction of CD8 T Cell Response Specific for Virally Derived H60
CD40-CD40L-mediated help from CD4 T cells is essential to induce primary CD8 T cell responses specific to the non-inflammatory cell-based antigen H60. In this study, using H60 as a model antigen, we generated recombinant vaccinia viruses (rVVs) expressing the H60 CD8 epitope and investigated whether...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422710/ https://www.ncbi.nlm.nih.gov/pubmed/22916048 http://dx.doi.org/10.4110/in.2012.12.3.118 |