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Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering
Recent successes in clinical trials have provided important proof of concept that small interfering RNAs (siRNAs) indeed constitute a new promising class of therapeutics. Although great efforts are still needed to ensure efficient means of delivery in vivo, the siRNA molecule itself has been success...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422727/ https://www.ncbi.nlm.nih.gov/pubmed/22934103 http://dx.doi.org/10.3389/fgene.2012.00154 |