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Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo
BACKGROUND AND METHODS: Paclitaxel, a widely used antitumor agent, has limited clinical application due to its hydrophobicity and systemic toxicity. To achieve sustained and targeted delivery of paclitaxel to tumor sites, liposomes composed of egg phosphatidylcholine, cholesterol, and distearolyphos...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423151/ https://www.ncbi.nlm.nih.gov/pubmed/22923988 http://dx.doi.org/10.2147/IJN.S32817 |