Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo

BACKGROUND AND METHODS: Paclitaxel, a widely used antitumor agent, has limited clinical application due to its hydrophobicity and systemic toxicity. To achieve sustained and targeted delivery of paclitaxel to tumor sites, liposomes composed of egg phosphatidylcholine, cholesterol, and distearolyphos...

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Detalles Bibliográficos
Autores principales: Cai, Lulu, Wang, Xianhuo, Wang, Wenwen, Qiu, Neng, Wen, Jiaolin, Duan, Xingmei, Li, Xia, Chen, Xiang, Yang, Li, Qian, Zhiyong, Wei, Yuquan, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423151/
https://www.ncbi.nlm.nih.gov/pubmed/22923988
http://dx.doi.org/10.2147/IJN.S32817

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