Effects of pH-sensitive chain length on release of doxorubicin from mPEG-b-PH-b-PLLA nanoparticles

BACKGROUND: Two methoxyl poly(ethylene glycol)-poly(L-histidine)-poly(L-lactide) (mPEG-PH-PLLA) triblock copolymers with different poly(L-histidine) chain lengths were synthesized. The morphology and biocompatibility of these self-assembled nanoparticles was investigated. METHODS: Doxorubicin, an an...

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Detalles Bibliográficos
Autores principales: Liu, Rong, He, Bin, Li, Dong, Lai, Yusi, Chang, Jing, Tang, James Z, Gu, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423155/
https://www.ncbi.nlm.nih.gov/pubmed/22923987
http://dx.doi.org/10.2147/IJN.S32053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423155/
https://www.ncbi.nlm.nih.gov/pubmed/22923987
http://dx.doi.org/10.2147/IJN.S32053

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