Protection by glia-conditioned medium in a cell model of Huntington disease

The physiological role of huntingtin and the pathogenic mechanisms that produce the disease are unknown. Mutant huntingtin changes its normal localization and produces cytoplasmic and intranuclear inclusions, changes gene transcription, alters synaptic transmission, impairs mitochondrial activity an...

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Detalles Bibliográficos
Autores principales: Ruiz, Carolina, Casarejos, Maria Jose, Gomez, Ana, Solano, Rosa, de Yebenes, Justo Garcia, Mena, Maria Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Molecular/Cellular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423315/
https://www.ncbi.nlm.nih.gov/pubmed/22919565
http://dx.doi.org/10.1371/4fbca54a2028b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423315/
https://www.ncbi.nlm.nih.gov/pubmed/22919565
http://dx.doi.org/10.1371/4fbca54a2028b

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