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AID Enzymatic Activity Is Inversely Proportional to the Size of Cytosine C5 Orbital Cloud
Activation induced deaminase (AID) deaminates cytosine to uracil, which is required for a functional humoral immune system. Previous work demonstrated, that AID also deaminates 5-methylcytosine (5 mC). Recently, a novel vertebrate modification (5-hydroxymethylcytosine - 5 hmC) has been implicated in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423351/ https://www.ncbi.nlm.nih.gov/pubmed/22916236 http://dx.doi.org/10.1371/journal.pone.0043279 |