Natural Iminosugar (+)-Lentiginosine Inhibits ATPase and Chaperone Activity of Hsp90

Heat shock protein 90 (Hsp90) is a significant target in the development of rational cancer therapy due to its role at the crossroads of multiple signaling pathways associated with cell proliferation and cell viability. The relevance of Hsp90 as a therapeutic target for numerous diseases states has...

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Detalles Bibliográficos
Autores principales: Dal Piaz, Fabrizio, Vassallo, Antonio, Chini, Maria Giovanna, Cordero, Franca M., Cardona, Francesca, Pisano, Claudio, Bifulco, Giuseppe, De Tommasi, Nunziatina, Brandi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423353/
https://www.ncbi.nlm.nih.gov/pubmed/22916240
http://dx.doi.org/10.1371/journal.pone.0043316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423353/
https://www.ncbi.nlm.nih.gov/pubmed/22916240
http://dx.doi.org/10.1371/journal.pone.0043316

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