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T Cell Receptor-Like Recognition of Tumor In Vivo by Synthetic Antibody Fragment
A major difficulty in treating cancer is the inability to differentiate between normal and tumor cells. The immune system differentiates tumor from normal cells by T cell receptor (TCR) binding of tumor-associated peptides bound to Major Histocompatibility Complex (pMHC) molecules. The peptides, der...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423377/ https://www.ncbi.nlm.nih.gov/pubmed/22916301 http://dx.doi.org/10.1371/journal.pone.0043746 |