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Activated Protein C Has a Protective Effect against Myocardial I/R Injury by Improvement of Endothelial Function and Activation of AKT1

OBJECTIVES: Activated protein C (APC) has a protective efficacy against ischemia-reperfusion (I/R) injury in several organs. The objective of this study was to investigate effect of APC in myocardium with possible mechanism. METHODS: We used regional and global myocardial I/R injury models of rats....

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Detalles Bibliográficos
Autores principales: Maehata, Yoshito, Miyagawa, Shigeru, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423409/
https://www.ncbi.nlm.nih.gov/pubmed/22916090
http://dx.doi.org/10.1371/journal.pone.0038738