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Activated Protein C Has a Protective Effect against Myocardial I/R Injury by Improvement of Endothelial Function and Activation of AKT1
OBJECTIVES: Activated protein C (APC) has a protective efficacy against ischemia-reperfusion (I/R) injury in several organs. The objective of this study was to investigate effect of APC in myocardium with possible mechanism. METHODS: We used regional and global myocardial I/R injury models of rats....
Autores principales: | Maehata, Yoshito, Miyagawa, Shigeru, Sawa, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423409/ https://www.ncbi.nlm.nih.gov/pubmed/22916090 http://dx.doi.org/10.1371/journal.pone.0038738 |
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