Analysis of MDM2 and MDM4 Single Nucleotide Polymorphisms, mRNA Splicing and Protein Expression in Retinoblastoma

Retinoblastoma is a childhood cancer of the developing retina that begins in utero and is diagnosed in the first years of life. Biallelic RB1 gene inactivation is the initiating genetic lesion in retinoblastoma. The p53 gene is intact in human retinoblastoma but the pathway is believed to be suppres...

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Detalles Bibliográficos
Autores principales: McEvoy, Justina, Ulyanov, Anatoly, Brennan, Rachel, Wu, Gang, Pounds, Stanley, Zhang, Jinghui, Dyer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423419/
https://www.ncbi.nlm.nih.gov/pubmed/22916154
http://dx.doi.org/10.1371/journal.pone.0042739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423419/
https://www.ncbi.nlm.nih.gov/pubmed/22916154
http://dx.doi.org/10.1371/journal.pone.0042739

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