(S)-α-Chlorohydrin Inhibits Protein Tyrosine Phosphorylation through Blocking Cyclic AMP - Protein Kinase A Pathway in Spermatozoa

α-Chlorohydrin is a common contaminant in food. Its (S)-isomer, (S)-α-chlorohydrin (SACH), is known for causing infertility in animals by inhibiting glycolysis of spermatozoa. The aim of present work was to examine the relationship between SACH and protein tyrosine phosphorylation (PTP), which plays...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Yu, Huan, Wang, Xia, Zheng, Weiwei, Yang, Bei, Pi, Jingbo, He, Gengsheng, Qu, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423423/
https://www.ncbi.nlm.nih.gov/pubmed/22916194
http://dx.doi.org/10.1371/journal.pone.0043004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423423/
https://www.ncbi.nlm.nih.gov/pubmed/22916194
http://dx.doi.org/10.1371/journal.pone.0043004

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