Cargando…
(S)-α-Chlorohydrin Inhibits Protein Tyrosine Phosphorylation through Blocking Cyclic AMP - Protein Kinase A Pathway in Spermatozoa
α-Chlorohydrin is a common contaminant in food. Its (S)-isomer, (S)-α-chlorohydrin (SACH), is known for causing infertility in animals by inhibiting glycolysis of spermatozoa. The aim of present work was to examine the relationship between SACH and protein tyrosine phosphorylation (PTP), which plays...
Autores principales: | Zhang, Hao, Yu, Huan, Wang, Xia, Zheng, Weiwei, Yang, Bei, Pi, Jingbo, He, Gengsheng, Qu, Weidong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423423/ https://www.ncbi.nlm.nih.gov/pubmed/22916194 http://dx.doi.org/10.1371/journal.pone.0043004 |
Ejemplares similares
-
Spermatotoxic effects of α-chlorohydrin in rats
por: Kim, Sung-Hwan, et al.
Publicado: (2012) -
Identification and Function of Exchange Proteins Activated Directly by Cyclic AMP (Epac) in Mammalian Spermatozoa
por: Miro-Moran, Alvaro, et al.
Publicado: (2012) -
From Symmetric Glycerol Derivatives to Dissymmetric Chlorohydrins
por: Solarte, Carmen, et al.
Publicado: (2011) -
Impact of 5'-amp-activated Protein Kinase on Male Gonad and Spermatozoa Functions
por: Nguyen, Thi Mong Diep
Publicado: (2017) -
Roles of Intracellular Cyclic AMP Signal Transduction in the Capacitation
and Subsequent Hyperactivation of Mouse and Boar Spermatozoa
por: HARAYAMA, Hiroshi
Publicado: (2013)