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Role of TRPM2 in H(2)O(2)-Induced Cell Apoptosis in Endothelial Cells

Melastatin-like transient receptor potential channel 2 (TRPM2) is an oxidant-sensitive and cationic non-selective channel that is expressed in mammalian vascular endothelium. Here we investigated the functional role of TRPM2 channels in hydrogen peroxide (H(2)O(2))-induced cytosolic Ca(2+) ([Ca(2+)]...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Yau, Ho-Yan, Wong, Wei-Yan, Li, Ronald A., Huang, Yu, Yao, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423428/
https://www.ncbi.nlm.nih.gov/pubmed/22916222
http://dx.doi.org/10.1371/journal.pone.0043186