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Classical HLA-DRB1 and DPB1 Alleles Account for HLA Associations with Primary Biliary Cirrhosis

Susceptibility to primary biliary cirrhosis (PBC) is strongly associated with HLA region polymorphisms. To determine if associations can be explained by classical HLA determinants we studied Italian 676 cases and 1440 controls with genotyped with dense single nucleotide polymorphisms (SNPs) for whic...

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Detalles Bibliográficos
Autores principales: Invernizzi, Pietro, Ransom, Michael, Raychaudhuri, Soumya, Kosoy, Roman, Lleo, Ana, Shigeta, Russell, Franke, Andre, Bossa, Fabrizio, Amos, Christopher I., Gregersen, Peter K., Siminovitch, Katherine A., Cusi, Daniele, de Bakker, Paul I.W., Podda, Mauro, Gershwin, M. Eric, Seldin, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423484/
https://www.ncbi.nlm.nih.gov/pubmed/22573116
http://dx.doi.org/10.1038/gene.2012.17