HEPARIN-BINDING EGF-LIKE GROWTH FACTOR PROMOTES EPITHELIAL-MESENCHYMAL TRANSITION IN HUMAN KERATINOCYTES

We have shown that autocrine proliferation of human keratinocytes (KC) is strongly dependent upon amphiregulin (AREG), whereas blockade of heparin-binding EGF-like growth factor (HB-EGF) inhibits KC migration in scratch wound assays. Here we demonstrate that expression of soluble HB-EGF (sHB-EGF) or...

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Detalles Bibliográficos
Autores principales: Stoll, Stefan W., Rittié, Laure, Johnson, Jessica L., Elder, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423535/
https://www.ncbi.nlm.nih.gov/pubmed/22592159
http://dx.doi.org/10.1038/jid.2012.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423535/
https://www.ncbi.nlm.nih.gov/pubmed/22592159
http://dx.doi.org/10.1038/jid.2012.78

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