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Frequent MGMT (0(6)-methylguanine-DNA methyltransferase) hypermethylation in long-term survivors of glioblastoma: a single institution experience

BACKGROUND: The aim of this retrospective study was to analyse the MGMT (0(6)-methylguanine-DNA methyltransferase) promoter methylation status in long-term surviving (≥ 3 years) patients with glioblastoma multiforme (GBM). METHODS: The methylation status of the MGMT promoter was determined by bisulf...

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Detalles Bibliográficos
Autores principales: Baur, Martina, Preusser, Matthias, Piribauer, Maria, Elandt, Katarzyna, Hassler, Marco, Hudec, Marcus, Dittrich, Christian, Marosi, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita, Warsaw 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423688/
https://www.ncbi.nlm.nih.gov/pubmed/22933901
http://dx.doi.org/10.2478/v10019-010-0023-y