Evolutionarily Repurposed Networks Reveal the Well-Known Antifungal Drug Thiabendazole to Be a Novel Vascular Disrupting Agent

Studies in diverse organisms have revealed a surprising depth to the evolutionary conservation of genetic modules. For example, a systematic analysis of such conserved modules has recently shown that genes in yeast that maintain cell walls have been repurposed in vertebrates to regulate vein and art...

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Detalles Bibliográficos
Autores principales: Cha, Hye Ji, Byrom, Michelle, Mead, Paul E., Ellington, Andrew D., Wallingford, John B., Marcotte, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423972/
https://www.ncbi.nlm.nih.gov/pubmed/22927795
http://dx.doi.org/10.1371/journal.pbio.1001379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423972/
https://www.ncbi.nlm.nih.gov/pubmed/22927795
http://dx.doi.org/10.1371/journal.pbio.1001379

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