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Effect of rubbing on the in vitro skin permeation of diclofenac-diethylamine 1.16% gel

BACKGROUND: Rubbing a topical NSAID (non steroidal anti-inflammatory drug) on the skin may increase local drug permeation, affecting its distribution to the site of pain and inflammation. The present study evaluates this hypothesis, by assessing in vitro the effect on skin permeation of applying dic...

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Detalles Bibliográficos
Autores principales: Hasler-Nguyen, Nathalie, Fotopoulos, Grigorios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424122/
https://www.ncbi.nlm.nih.gov/pubmed/22720797
http://dx.doi.org/10.1186/1756-0500-5-321