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Expression of Eukaryotic Initiation Factor 5A and Hypusine Forming Enzymes in Glioblastoma Patient Samples: Implications for New Targeted Therapies

Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demonstrated that the posttranslational hypusine modif...

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Detalles Bibliográficos
Autores principales: Preukschas, Michael, Hagel, Christian, Schulte, Alexander, Weber, Kristoffer, Lamszus, Katrin, Sievert, Henning, Pällmann, Nora, Bokemeyer, Carsten, Hauber, Joachim, Braig, Melanie, Balabanov, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424167/
https://www.ncbi.nlm.nih.gov/pubmed/22927971
http://dx.doi.org/10.1371/journal.pone.0043468