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A Switch Role of Src in the Biphasic EGF Signaling of ER-Negative Breast Cancer Cells
It is well established that epidermal growth factor (EGF) is a potent mitogen in cells expressing EGF receptor (EGFR). However, a body of evidence indicated that the effects of mitogenic EGF signaling exhibit a non-monotonic, or biphasic dose response curve; EGF at low concentrations elicits a mitog...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424221/ https://www.ncbi.nlm.nih.gov/pubmed/22927910 http://dx.doi.org/10.1371/journal.pone.0041613 |