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A Switch Role of Src in the Biphasic EGF Signaling of ER-Negative Breast Cancer Cells

It is well established that epidermal growth factor (EGF) is a potent mitogen in cells expressing EGF receptor (EGFR). However, a body of evidence indicated that the effects of mitogenic EGF signaling exhibit a non-monotonic, or biphasic dose response curve; EGF at low concentrations elicits a mitog...

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Detalles Bibliográficos
Autores principales:	Zhang, XinTian, Meng, Jun, Wang, Zhao-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424221/ https://www.ncbi.nlm.nih.gov/pubmed/22927910 http://dx.doi.org/10.1371/journal.pone.0041613

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