Multi-Target Regulation by Small RNAs Synchronizes Gene Expression Thresholds and May Enhance Ultrasensitive Behavior

Cells respond to external cues by precisely coordinating multiple molecular events. Co-regulation may be established by the so-called single-input module (SIM), where a common regulator controls multiple targets. Using mathematical modeling, we compared the ability of SIM architectures to precisely...

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Detalles Bibliográficos
Autores principales: Schmiedel, Jörn Matthias, Axmann, Ilka Maria, Legewie, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424230/
https://www.ncbi.nlm.nih.gov/pubmed/22927924
http://dx.doi.org/10.1371/journal.pone.0042296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424230/
https://www.ncbi.nlm.nih.gov/pubmed/22927924
http://dx.doi.org/10.1371/journal.pone.0042296

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