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The Octadecaneuropeptide ODN Protects Astrocytes against Hydrogen Peroxide-Induced Apoptosis via a PKA/MAPK-Dependent Mechanism

Astrocytes synthesize and release endozepines, a family of regulatory peptides, including the octadecaneuropeptide (ODN) an endogenous ligand of both central-type benzodiazepine (CBR) and metabotropic receptors. We have recently shown that ODN exerts a protective effect against hydrogen peroxide (H(...

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Detalles Bibliográficos
Autores principales: Hamdi, Yosra, Kaddour, Hadhemi, Vaudry, David, Bahdoudi, Seyma, Douiri, Salma, Leprince, Jérôme, Castel, Helene, Vaudry, Hubert, Tonon, Marie-Christine, Amri, Mohamed, Masmoudi-Kouki, Olfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424241/
https://www.ncbi.nlm.nih.gov/pubmed/22927932
http://dx.doi.org/10.1371/journal.pone.0042498