Rapid incorporation kinetics and improved fidelity of a novel class of 3′-OH unblocked reversible terminators

Recent developments of unique nucleotide probes have expanded our understanding of DNA polymerase function, providing many benefits to techniques involving next-generation sequencing (NGS) technologies. The cyclic reversible termination (CRT) method depends on efficient base-selective incorporation...

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Detalles Bibliográficos
Autores principales: Gardner, Andrew F., Wang, Jinchun, Wu, Weidong, Karouby, Jennifer, Li, Hong, Stupi, Brian P., Jack, William E., Hersh, Megan N., Metzker, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424534/
https://www.ncbi.nlm.nih.gov/pubmed/22570423
http://dx.doi.org/10.1093/nar/gks330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424534/
https://www.ncbi.nlm.nih.gov/pubmed/22570423
http://dx.doi.org/10.1093/nar/gks330

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