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Rapid incorporation kinetics and improved fidelity of a novel class of 3′-OH unblocked reversible terminators
Recent developments of unique nucleotide probes have expanded our understanding of DNA polymerase function, providing many benefits to techniques involving next-generation sequencing (NGS) technologies. The cyclic reversible termination (CRT) method depends on efficient base-selective incorporation...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424534/ https://www.ncbi.nlm.nih.gov/pubmed/22570423 http://dx.doi.org/10.1093/nar/gks330 |