Active site opening and closure control translocation of multisubunit RNA polymerase

Multisubunit RNA polymerase (RNAP) is the central information-processing enzyme in all cellular life forms, yet its mechanism of translocation along the DNA molecule remains conjectural. Here, we report direct monitoring of bacterial RNAP translocation following the addition of a single nucleotide....

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Detalles Bibliográficos
Autores principales: Malinen, Anssi M., Turtola, Matti, Parthiban, Marimuthu, Vainonen, Lioudmila, Johnson, Mark S., Belogurov, Georgiy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424550/
https://www.ncbi.nlm.nih.gov/pubmed/22570421
http://dx.doi.org/10.1093/nar/gks383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424550/
https://www.ncbi.nlm.nih.gov/pubmed/22570421
http://dx.doi.org/10.1093/nar/gks383

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