Tracing the path of DNA substrates in active Tetrahymena telomerase holoenzyme complexes: mapping of DNA contact sites in the RNA subunit

Telomerase, the enzyme that extends single-stranded telomeric DNA, consists of an RNA subunit (TER) including a short template sequence, a catalytic protein (TERT) and accessory proteins. We used site-specific UV cross-linking to map the binding sites for DNA primers in TER within active Tetrahymena...

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Detalles Bibliográficos
Autores principales: Goldin, Svetlana, Kertesz Rosenfeld, Karin, Manor, Haim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424564/
https://www.ncbi.nlm.nih.gov/pubmed/22584626
http://dx.doi.org/10.1093/nar/gks416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424564/
https://www.ncbi.nlm.nih.gov/pubmed/22584626
http://dx.doi.org/10.1093/nar/gks416

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