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Measurements of DNA-loop formation via Cre-mediated recombination

The Cre-recombination system has become an important tool for genetic manipulation of higher organisms and a model for site-specific DNA-recombination mechanisms employed by the λ-Int superfamily of recombinases. We report a novel quantitative approach for characterizing the probability of DNA-loop...

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Detalles Bibliográficos
Autores principales: Shoura, Massa J., Vetcher, Alexandre A., Giovan, Stefan M., Bardai, Farah, Bharadwaj, Anusha, Kesinger, Matthew R., Levene, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424569/
https://www.ncbi.nlm.nih.gov/pubmed/22589415
http://dx.doi.org/10.1093/nar/gks430