A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens

Many carcinogens leave a unique mutational fingerprint in the human genome. These mutational fingerprints manifest as specific types of mutations often clustering at certain genomic loci in tumor genomes from carcinogen-exposed individuals. To develop a high-throughput method for detecting the mutat...

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Detalles Bibliográficos
Autores principales: Besaratinia, Ahmad, Li, Haiqing, Yoon, Jae-In, Zheng, Albert, Gao, Hanlin, Tommasi, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424585/
https://www.ncbi.nlm.nih.gov/pubmed/22735701
http://dx.doi.org/10.1093/nar/gks610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424585/
https://www.ncbi.nlm.nih.gov/pubmed/22735701
http://dx.doi.org/10.1093/nar/gks610

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