Cargando…
A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens
Many carcinogens leave a unique mutational fingerprint in the human genome. These mutational fingerprints manifest as specific types of mutations often clustering at certain genomic loci in tumor genomes from carcinogen-exposed individuals. To develop a high-throughput method for detecting the mutat...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424585/ https://www.ncbi.nlm.nih.gov/pubmed/22735701 http://dx.doi.org/10.1093/nar/gks610 |