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Multicomponent Assembly of Proposed DNA Precursors in Water

[Image: see text] We propose a novel pathway for the prebiotic synthesis of 2′-deoxynucleotides. Consideration of the constitutional chemical relationships between glycolaldehyde and β-mercapto-acetaldehyde, and the corresponding proteinogenic amino acids, serine and cysteine, led us to explore the...

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Detalles Bibliográficos
Autores principales: Powner, Matthew W., Zheng, Shao-Liang, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424849/
https://www.ncbi.nlm.nih.gov/pubmed/22839703
http://dx.doi.org/10.1021/ja306176n