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The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment

[Image: see text] Mammalian Nod2 is an intracellular protein that is implicated in the innate immune response to the bacterial cell wall and is associated with the development of Crohn’s disease, Blau syndrome, and gastrointestinal cancers. Nod2 is required for an immune response to muramyl dipeptid...

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Detalles Bibliográficos
Autores principales: Grimes, Catherine Leimkuhler, Ariyananda, Lushanti De Zoysa, Melnyk, James E., O’Shea, Erin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424850/
https://www.ncbi.nlm.nih.gov/pubmed/22857257
http://dx.doi.org/10.1021/ja303883c