Administration of CD4(+)CD25(high)CD127(−) Regulatory T Cells Preserves β-Cell Function in Type 1 Diabetes in Children

OBJECTIVE: Type 1 diabetes is a condition in which pancreatic islets are destroyed by self-reactive T cells. The process is facilitated by deficits in the number and suppressive activity of regulatory T cells (Tregs). Here, we show for the first time that the infusion of autologous Tregs prolongs re...

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Detalles Bibliográficos
Autores principales: Marek-Trzonkowska, Natalia, Myśliwiec, MaŁgorzata, Dobyszuk, Anita, Grabowska, Marcelina, Techmańska, Ilona, Juścińska, Jolanta, Wujtewicz, Magdalena A., Witkowski, Piotr, Młynarski, Wojciech, Balcerska, Anna, Myśliwska, Jolanta, Trzonkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425004/
https://www.ncbi.nlm.nih.gov/pubmed/22723342
http://dx.doi.org/10.2337/dc12-0038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425004/
https://www.ncbi.nlm.nih.gov/pubmed/22723342
http://dx.doi.org/10.2337/dc12-0038

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