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A Validated HPLC Method for Zanamivir and its Application to In vitro Permeability Study in Caco-2 Culture Model

A simple HPLC method was developed and validated for the quantification of zanamivir in permeability studies using Caco-2 cell culture model. Chromatographic resolution was achieved using 98% (v/v) ultrapure water and 2% (v/v) acetonitrile as mobile phase with flow rate of 0.5 ml/min on a BDS Hypers...

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Detalles Bibliográficos
Autores principales: Boonyapiwat, B., Sarisuta, N., Ma, Y., Steventon, G. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425069/
https://www.ncbi.nlm.nih.gov/pubmed/22923870
http://dx.doi.org/10.4103/0250-474X.99015