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Enhancement of Th1-biased protective immunity against avian influenza H9N2 virus via oral co-administration of attenuated Salmonella enterica serovar Typhimurium expressing chicken interferon-α and interleukin-18 along with an inactivated vaccine

BACKGROUND: Control of currently circulating re-assorted low-pathogenicity avian influenza (LPAI) H9N2 is a major concern for both animal and human health. Thus, an improved LPAI H9N2 vaccination strategy is needed to induce complete immunity in chickens against LPAI H9N2 virus strains. Cytokines pl...

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Detalles Bibliográficos
Autores principales: Rahman, Md Masudur, Uyangaa, Erdenebileg, Han, Young Woo, Kim, Seong Bum, Kim, Jin Hyoung, Choi, Jin Young, Eo, Seong Kug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425080/
https://www.ncbi.nlm.nih.gov/pubmed/22776696
http://dx.doi.org/10.1186/1746-6148-8-105