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A novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids

AIMS: A novel robust chiral gas chromatographic/mass spectrometric (GC/MS) method for the separation and measurement of fluoxetine and norfluoxetine enantiomers in urine and plasma was developed. MATERIALS AND METHODS: The drug was extracted from the samples by a liquid–liquid technique, using chlor...

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Detalles Bibliográficos
Autores principales: Mifsud, Janet, Sghendo, Lino J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425174/
https://www.ncbi.nlm.nih.gov/pubmed/22923967
http://dx.doi.org/10.4103/0975-7406.99065