Cargando…

A novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids

AIMS: A novel robust chiral gas chromatographic/mass spectrometric (GC/MS) method for the separation and measurement of fluoxetine and norfluoxetine enantiomers in urine and plasma was developed. MATERIALS AND METHODS: The drug was extracted from the samples by a liquid–liquid technique, using chlor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mifsud, Janet, Sghendo, Lino J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425174/ https://www.ncbi.nlm.nih.gov/pubmed/22923967 http://dx.doi.org/10.4103/0975-7406.99065

Ejemplares similares

Serum fluoxetine and norfluoxetine levels support the safety of fluoxetine in overdose
por: Pope, Stephanie, et al.
Publicado: (2016)

Oxidative and Apoptotic Effects of Fluoxetine and Its Metabolite Norfluoxetine in Daphnia Magna
por: Över, Sevgi Başalan, et al.
Publicado: (2020)

The Herb-Drug Pharmacokinetic Interaction of Fluoxetine and Its Metabolite Norfluoxetine with a Traditional Chinese Medicine in Rats by LC-MS/MS
por: Yan, Lijing, et al.
Publicado: (2019)

Determination of 2-Pentanol Enantiomers via Chiral GC-MS and Its Sensory Evaluation in Baijiu
por: Hu, Lisha, et al.
Publicado: (2022)

Factors associated with fluoxetine and norfluoxetine plasma concentrations and clinical response in Mexican patients with mental disorders
por: Sagahón‐Azúa, Julia, et al.
Publicado: (2021)

An Innovative Chiral UPLC-MS/MS Method for Enantioselective Determination and Dissipation in Soil of Fenpropidin Enantiomers
por: Li, Rui, et al.
Publicado: (2022)

Determination of the Effect of Wastewater on the Biological Activity of Mixtures of Fluoxetine and Its Metabolite Norfluoxetine with Nalidixic and Caffeic Acids with Use of E. coli Microbial Bioindicator Strains
por: Matejczyk, Marzena, et al.
Publicado: (2023)

In vitro modulation of estrogen receptor activity by norfluoxetine
por: LUPU, DIANA, et al.
Publicado: (2015)

Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers
por: Tokunaga, Etsuko, et al.
Publicado: (2018)

Effects of norfluoxetine and venlafaxine in zebrafish larvae: Molecular data
por: Rodrigues, Pedro, et al.
Publicado: (2020)

Simultaneous Quantitative Determination of Synthetic Cathinone Enantiomers in Urine and Plasma Using GC-NCI-MS
por: Alremeithi, Rashed, et al.
Publicado: (2018)

Comment on Hu et al. Determination of 2-Pentanol Enantiomers via Chiral GC-MS and Its Sensory Evaluation in Baijiu. Foods 2022, 11, 2584
por: Frański, Rafał
Publicado: (2023)

Chiral Separation of the Phenylglycinol Enantiomers by Stripping Crystallization
por: Shiau, Lie-Ding
Publicado: (2018)

Strategies for chiral separation: from racemate to enantiomer
por: Sui, Jingchen, et al.
Publicado: (2023)

Development of a chiral HPLC method for the separation and quantification of hydroxychloroquine enantiomers
por: Xiong, Xisheng, et al.
Publicado: (2021)

Reply to Frański, R. Comment on “Hu et al. Determination of 2-Pentanol Enantiomers via Chiral GC-MS and Its Sensory Evaluation in Baijiu. Foods 2022, 11, 2584”
por: Hu, Lisha, et al.
Publicado: (2023)

Chirality detection of enantiomers using twisted optical metamaterials
por: Zhao, Yang, et al.
Publicado: (2017)

Enantiomer-selective magnetization of conglomerates for quantitative chiral separation
por: Ye, Xichong, et al.
Publicado: (2019)

Chiral Discrimination of Mexiletine Enantiomers by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors and Experimental Design Method Optimization
por: Cârcu-Dobrin, Melania, et al.
Publicado: (2022)

Fluoxetine and norfluoxetine mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19 and CYP3A4
por: Sager, Jennifer E, et al.
Publicado: (2014)

Synthesis of Pure Enantiomers of Titanium(IV) Complexes with Chiral Diaminobis(phenolato) Ligands and Their Biological Reactivity
por: Miller, Maya, et al.
Publicado: (2018)

Authenticity of raspberry flavor in food products using SPME‐chiral‐GC‐MS
por: Hansen, Anne‐Mette S., et al.
Publicado: (2015)

Chirality of the biomolecules enhanced its stereospecific action of dihydromyricetin enantiomers
por: Umair, Muhammad, et al.
Publicado: (2020)

Essential Oil Composition Analysis of Cymbopogon Species from Eastern Nepal by GC-MS and Chiral GC-MS, and Antimicrobial Activity of Some Major Compounds
por: Dangol, Sabita, et al.
Publicado: (2023)

Separation of Alkyne Enantiomers by Chiral Column HPLC Analysis of Their Cobalt-Complexes
por: Liu, Qiaoyun, et al.
Publicado: (2017)

Quantum interference directed chiral raman scattering in two-dimensional enantiomers
por: Zhang, Shishu, et al.
Publicado: (2022)

Rotaxanes with dynamic mechanical chirality: Systematic studies on synthesis, enantiomer separation, racemization, and chiral-prochiral interconversion
por: Ishiwari, Fumitaka, et al.
Publicado: (2022)

Quality by Design Assisted Optimization of a Chiral Capillary Electrokinetic Chromatographic Method for the Separation of Amlodipine Enantiomers Using Maltodextrin as Chiral Selector
por: Ratih, Ratih, et al.
Publicado: (2022)

Enantioselectivity-Evaluation of Chiral Copper(II) Complexes Coordinated by Novel Chiral Tetradentate Ligands for Free Amino Acids by Mass Spectrometry Coupled With the Isotopically Labeled Enantiomer Method
por: Nakakoji, Takashi, et al.
Publicado: (2020)

Determination of tobacco alkaloid enantiomers using reversed phase UPLC/MS/MS
por: Ji, Huihua, et al.
Publicado: (2019)

Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application
por: Ou, Fengting, et al.
Publicado: (2020)

G-Quadruplex binding enantiomers show chiral selective interactions with human telomere
por: Wang, Jiasi, et al.
Publicado: (2014)

Engineering Cyclodextrin Clicked Chiral Stationary Phase for High-Efficiency Enantiomer Separation
por: Tang, Jian, et al.
Publicado: (2015)

Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol
por: Sparaco, Rosa, et al.
Publicado: (2022)

Swim in the Chiral Pool: MDMA and MDA Enantiomers from Alanine-Derived Precursors
por: Sherwood, Alexander M., et al.
Publicado: (2023)

Selective and comprehensive analysis of organohalogen compounds by GC × GC–HRTofMS and MS/MS
por: Hashimoto, Shunji, et al.
Publicado: (2015)

Chiral Separation of Oxazolidinone Analogs by Capillary Electrophoresis Using Anionic Cyclodextrins as Chiral Selectors: Emphasis on Enantiomer Migration Order
por: Szabó, Zoltán-István, et al.
Publicado: (2023)

Multianalytical Method Validation for Qualitative and Quantitative Analysis of Solvents of Abuse in Oral Fluid by HS-GC/MS
por: Coppe, Bruna Claudia, et al.
Publicado: (2016)

Biological analysis on extractives of bayberry fresh flesh by GC–MS
por: Ge, Shengbo, et al.
Publicado: (2018)

A colour-tunable chiral AIEgen: reversible coordination, enantiomer discrimination and morphology visualization
por: Roose, Jesse, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_acudn0tmnf2qdroon2pfl96pko